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Laura Curiel, Ph.D.

profile image placeholder, grey silhouette of a person Northern Ontario School of Medicine
Lakehead University
955 Oliver Road
Thunder Bay ON  P7B 5E1  Canada
Associate Professor, Northern Ontario School of Medicine, Medical Sciences Division
Scientist, Thunder Bay Regional Research Institute
Adjunct Professor, Department of Electrical Engineering, Department of Physics, Lakehead University
Member: ECE Master’s program, Physics Master’s program, Biotechnology PhD program, Lakehead University



Post-Doctoral Fellowship; Department of Imaging Research, Focused Ultrasound Laboratory
Sunnybrook Research Institute – Toronto (Toronto, ON)


Post-Doctoral Fellowship; Unite 556, Therapeutic Ultrasound
French Institute of Health and Medical Research (INSERM) – Lyon (Lyon, France)


Ph.D.; Imaging and Systems, EEA program, Faculty of Engineering
Institut National de Sciences Appliquées de Lyon (Lyon, France)


Master’s Eq (DEA); Biomedical Engineering
Faculty of Sciences and Engineering, University of Lyon (Lyon, France)


B. Eng.; Electronic Systems Engineering, Faculty of Engineering
Monterrey Institute of Technology and Higher Education (Estado de Mexico, Mexico)

Research Investigations

My current interests include:

  • Non invasive therapy using high intensity focused ultrasound (HIFU)
  • Ultrasound and Magnetic Resonance Imaging
  • Molecule delivery using ultrasound
  • Clinical parameters optimization for HIFU applications
  • Clinical applications for HIFU applications (uterine fibroids treatment, bone metastasis pain palliation)
  • Development and experimentation of new FUS devices
  • Biomedical Acoustics and Modeling

Dr. Curiel may have positions available for undergraduate or graduate students, depending on funding.

Selected Publications

Pichardo S, Melodelima D, Curiel L, “Suitability of MR guided focused ultrasound treatment using a tumour-mimic model”, Phys Med Biol. 2013 Mar 8;58(7):2163-2183.

Curiel L, Hobson D, Chapelon JY, Pichardo S, “High Intensity Focused Ultrasound Optimal Device Design for Targeted Prostate Cancer Treatment: A Numerical Study,” J Mod Phys, 2013, 4:240-45.

Pichardo S, Togtema M, Pulkki K, Zehbe I and Curiel L, Influence of cell line and cell cycle phase on sonoporation transfection efficiency in cervical carcinoma cells under the same physical conditions, IEEE Ultrasound Ferroelec and Freq Ctrl, 2013, 60(2):Feb2013.

Ahmed SJ, Kivinen J, Zaporzan B, Curiel L, Pichardo S, Rubel O, BerryPI: A software for studying polarization of crystalline solids with WIEN2k density functional all-electron package, Computer Physics Communications 2012,184:647-651.

Togtema M, Pichardo S, Jackson R, Curiel L, Zehbe I, “Sonoporation Delivery of Monoclonal Antibodies against Human Papillomavirus 16 E6 Restores p53 Expression in Transformed Cervical Keratinocytes” PLOS-One 2012,7(11): e50730.

Curiel L, Hynynen K, Localized Harmonic Motion Imaging for Focused Ultrasound Surgery Targeting, Ultrasound Med Biol, submitted.

Heikkila J, Curiel L, Hynynen K, Local Harmonic Motion Monitoring of Focused Ultrasound Surgery – a Simulation Model, Trans. Biomed. Eng., 2009, 57(1):185-93.

Curiel L, Huang Y, Vykhodtseva N, Hynynen K, Local Harmonic Motion Imaging as Control for Focused Ultrasound Surgery: VX2 Tumor Study, Phys. Med. Biol. 2009, 54(11):3405-19.

Chopra R, Curiel L, Staruch R, Morrison L, Hynynen K, An MRI-Compatible System for Focused Ultrasound Experiments in Small Animal Models, Med. Phys. 2009,36(5):1867-1874.

Pichardo S, Gelet A, Curiel L, Chesnais S, Chapelon JY, New Integrated Imaging High Intensity Focused Ultrasound Probe for Transrectal Prostate Cancer Treatment. Ultrasound Med & Biol, 2008,34(7):1105-16.

Curiel L, Chopra R, Hynynen K, Progress in Multimodality Imaging: Truly Simultaneous Ultrasound and Magnetic Resonance Imaging. IEEE Trans. on Medical Imaging, 2007, 26 (12): 1740-1746.

Poissonnier L, Chapelon JY, Rouviere O, Curiel L, Bouvier R, Martin X, Dubernard JM, Gelet A. Control of prostate cancer by transrectal HIFU in 227 patients. Eur Urol. 2007, 51(2):381-387.

Curiel L, Souchon R, Rouvière O, Gelet A, Chapelon JY. Elastography for the follow-up of High Intensity Focused Ultrasound prostate cancer treatment: Initial comparison with MRI. Ultrasound

Gelet A, Chapelon JY, Poissonnier L, Bouvier R, Rouvière O, Curiel L, Janier M, Vallancien G, Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using High-Intensity Focused Ultrasonography, Urology, 2004, 63 (4): 625-629.