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Jennifer Lemon

profile image placeholder, grey silhouette of a person Northern Ontario School of Medicine
Lakehead University
955 Oliver Road
Thunder Bay, ON Canada P7B5E1
Assistant Professor, Northern Ontario School of Medicine, Medical Sciences Division
Research Associate: Medical Physics and Applied Radiation Sciences, McMaster University

Education/Training

 2009-2013

Scientist; Discovery Core – Biology
Centre for Probe Development and Commercialization (Hamilton, ON)

 2007-2009

Post-Doctoral Fellowship; Department of Chemistry and Chemical Biology
Juravinski Cancer Centre/McMaster University (Hamilton, ON)

 2005-2007

Post-Doctoral Fellowship; Department of Medical Physics and Applied Radiation Sciences
McMaster University (Hamilton, ON)

1999-2005

Ph.D.; Molecular Immunology, Virology & Inflammation Program, Department of Biology
Faculty of Science, McMaster University (Hamilton, ON)

1992-1998

Hons. B.Sc.; Biology (complementary studies stream), minor in Neuroscience
McMaster University (Hamilton, ON)

Research Investigations

My current interests include:

  • effect of low dose radiation on biological systems;
  • the modulation of radiation-induced tissue damage by dietary supplements;
  • the use of dietary supplements to modulate aging and age-related diseases

Selected Publications

Lazarova N, Causey PW, Lemon JA, Czorny SK, Forbes JR, Zlitni A, Genady A, Foster FS, Valliant JF. The synthesis, magnetic purification and evaluation of 99mTc-labeled microbubbles. Nucl. Med. Biol. 38:1111-1118, 2011.

Beer ML, Lemon J, Valliant JF. Preparation and evaluation of carborane analogues of tamoxifen. J. Med. Chem. 53:8012-8020, 2010.

Armstrong AF, Lemon JA, Czorny SK, Singh G, Valliant JF. Evaluation of single amino acid chelate derivatives and regioselective radiolabelling of a cyclic peptide for the urokinase plasminogen activator receptor. Nucl. Med. Biol.36:907-917, 2009.

Parrott MC, Benhabbour SR, Saab C, Lemon JA, Parker S, Valliant JF, Adronov A. Synthesis, radiolabeling, and bio-imaging of high-generation polyester dendrimers. J. Am. Chem. Soc. 13:2906-2916, 2009.

Armstrong AF, Oakley N, Parker S, Causey PW, Lemon J, Capretta A, Zimmerman C, Joyal J, Appoh F, Zubieta J, Babich JW, Singh G, Valliant JF. A Robust Strategy for the Preparation of Libraries of Metallopeptides. A New Paradigm for the Discovery of Targeted Molecular Imaging and Therapy Agents. Chem. Commun. 43:5532-5534, 2008.

Lemon JA, Rollo CD, McFarlane NM, Boreham DR. Radiation-induced apoptosis in mouse lymphocytes is modified by a complex dietary supplement: the effect of genotype and gender. Mutagenesis. 23:465-472, 2008.

Lemon JA, Rollo CD, Boreham DR. Elevated DNA damage in a mouse model of oxidative stress: impacts of ionizing radiation and a protective dietary supplement. Mutagenesis. 23:473-482, 2008.

Kilemade M, Lemon JA, Boreham DR. Characteristics of the adaptive response in cultured salmon cells exposed to ionizing radiation. Environ. Mol. Mutagen. 49:165-172, 2008.

Schaffer P, Gleave JA, Lemon JA, Reid LC, Pacey LK, Farncombe TH, Boreham DR, Zubieta J, Babich JW, Doering LC, Valliant JF. Isostructural fluorescent and radioactive probes for monitoring neural stem and progenitor cell transplants. Nucl. Med. Biol. 35: 159-169, 2008.

Cassidy CL, Lemon JA, Boreham DR. Impacts of low-dose gamma-radiation on genotoxic risk in aquatic ecosystems. Dose Response. 5:323-332, 2007

Lemon JA, Boreham DR, Rollo CD. A dietary supplement extends longevity in mice.  J. Gerontol. A Biol. Sci. Med. Sci. 60A:275-279, 2005.

Stephenson KA, Banerjee SR, Besanger T, Sogbein OO, Levadala MK, McFarlane N, Lemon JA, Boreham DR, Maresca KP, Brennan JD, Babich JW, Zubieta J, Valliant JF. Bridging the gap between in vitro and in vivo imaging: isostructural Re and 99mTc complexes for correlating fluorescence and radioimaging studies. J. Am. Chem. Soc. 126:8598-8599, 2004

Rollo CD, Lai M, Whitehead K, Perreault ML, Lemon JA, Chaudhry AM. Thermoregulation of transgenic growth hormone mice. Can. J. Zool. 82:934-949, 2004.

Lemon JA, Boreham DR, Rollo CD. A dietary supplement abolishes age-related cognitive decline in transgenic mice expressing elevated free radical processes. Exp. Biol. Med. 228: 800-810, 2003

Lemon JA, Boreham DR. Workshop on networking radiation sciences in health, safety and the environment. Int. J. Rad. Biol. 80: 83-89, 2003