Professor, Medical Sciences Division
Lakehead University Campus
955 Oliver Road
Thunder Bay, Ontario
P7B 5E1
Phone: 807-766-7395
Fax: 807-766-7362
Email: zsuntres@nosm.ca
Education and Professional Roles
Professor, Pharmacology and Toxicology, Medical Sciences Division, Northern Ontario School of Medicine (NOSM)
Chair, Student Assessment and Promotions Committee, NOSM
Adjunct Professor, Department of Chemistry, Lakehead University
Member, Biotechnology Research Program, Lakehead University
Member, Biomolecular Sciences PhD Programme, Laurentian University
1992-2004: Defence Scientist, Defence and Civil Institute of Environmental Medicine
1990-1992: NSERC Post-Doctoral Fellow, Defence and Civil Institute of Environmental Medicine
1990: PhD, Department of Pharmacology and Toxicology, University of Western Ontario
1985: B.Sc., Department of Pharmacology and Toxicology, University of Western Ontario
Research Interest
Current interests include:
- Drug delivery systems for antioxidants and antimicrobial agents
- Role of thiols in oxidative stress
- Biological effects of extracts from plants and lichens
- Effects of ultra-low dose radiation on biological systems
Dr. Suntres may have positions available for undergraduate or graduate students, depending on funding.
Selected Publications
Suntres, Z.E., Exploring the potential benefit of natural product extracts in paraquat toxicity.
Fitoterapia, 131:160-167, 2018.
Yeash EA, Letwin L., Malek L,
Suntres Z, Knudsen K, Christopher LP. Biological Activities of Undescribed North American Lichen Species.
J Sci Food Agric. 97:4721-4726, 2017.
Coccimiglio, J., Alipour, M., Gottardo, C., Jiang, J., Pycko, R., Suntres, Z.E. Antioxidant, Antibacterial, and Cytotoxic Activities of the Ethanolic Origanum vulgare Extract and Its Major Constituents.
Oxid Med Cell Longev. 1404505. doi:10.1155/2016/1404505, 2016.
Suntres, Z.E., Coccimiglio, J., and Alipour, M. The bioactivity and toxicological actions of carvacrol.
Critical Reviews in Food Science and Nutrition. 55(3):304-318, 2015.
Kachur, K. and
Suntres, Z.E. The antimicrobial properties of ginseng and ginseng extracts.
Expert Review of Anti-infective Therapy, 14: 81-94, 2015.
Alipour, M. and
Suntres, ZE. Liposomal antibiotic formulations for targeting the lungs in the treatment of
Pseudomonas aeruginosa.
Ther Deliv. 5(4):409-427, 2014.
Suntres, Z.E., Smith GM, Hu J, Zhang, X, Wu, Y., Zhu, H., Wang, J., Zhou J., Kuo, W.P. Therapeutic uses of exosomes.
Exosomes and Microvesicles, Vol. 1, 4:2013.
Alipour, M., Pucaj, K., Smith, M.G., and
Suntres, Z.E. Safety and pharmacokinetic studies of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol and γ-tocopherol in beagle dogs.
Toxicol. Mech Methods 23(6):419-31, 2013.
Suntres, Z.E. The role of liposomal antioxidants in oxidant-induced injuries.
J Toxicol 2011:152474, 2011.
Suntres, Z.E. Role of antioxidants in paraquat toxicity.
Toxicology. 180: 65-77, 2002.
Alipour, M., Omri, A., Smith, MG, Suntres, Z.E. Liposomal N-Acetylcysteine protects against LPS-induced liver injuries in rats.
J. of Endotoxin Res. 13:297-304, 2007.
Alipour, M., Omri, A., Halwani, M., Suntres, Z.E. Liposomal Polymyxin B: Preparation, Characterization and Evaluation of its Activity towards Gram-negative Bacterial Strains.
Intern. J. Pharmaceut. 355:293-298, 2008.
Mitsopoulos, P., Alipour M., Omri A., Smith M.G., Suntres, Z.E. Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents.
Int. J Pharm. 363:106-111, 2008.
Halwani M., Yebio B.,
Suntres Z.E., Alipour M., Azghani A.O., Omri A.
Co-encapsulation of gallium with gentamicin in liposomes enhances antimicrobial activity of gentamicin against Pseudomonas aeruginosa.
Antimicrob Chemother. 62:1291-7, 2008.
Halwani, M., Hebert, S.,
Suntres, Z.E., Lafrenie, R.M., Azghani, A.O., Omri, A. Bismuth-thiol Incorporation Enhances Biological Activities of Liposomal Tobramycin against Bacterial Biofilm and Quorum Sensing Molecules Production by Pseudomonas aeruginosa.
International Journal of Pharmaceutics, 373:141-146, 2009.
Alipour, M.,
Suntres, Z.E., Omri, A. Importance of DNase and alginate lyase for enhancing free and liposome encapsulated aminoglycoside activity against Pseudomonas aeruginosa.
J Antimicrob Chemother. 64:317-325, 2009.
Alipour M.,
Suntres Z.E., Lafrenie R.M., Omri A. Attenuation of Pseudomonas Aeruginosa Virulence Factors and Biofilms by Co-encapsulation of Bismuth-ethanedithiol with Tobramycin in liposomes.
J Antimicrob Chemother. 65:684-693, 2010.
Mitsopoulos, P. &
Suntres, Z.E. Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat.
Chem Biol Interact. 188:427-436, 2010.