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Dr. David Marsh

Dr. Marsh is the Associate Dean Research, Innovation and International Relations at the Northern Ontario School of Medicine, Adjunct Scientist ICES North and Chief Medical Director for Canadian Addiction Treatment Centres. David graduated in Medicine from Memorial University of Newfoundland in 1992, following prior training in neuroscience and pharmacology. From July 2010 to Feb 2018, Dr. Marsh served NOSM as Associate Dean, Community Engagement.
Prior to moving to NOSM, David held leadership positions with Vancouver Coastal Health and Providence Health Care and faculty appointment with the Faculty of Medicine at the University of British Columbia from 2004-2010. Previously, he held leadership roles at the Addiction Research Foundation and the Centre for Addiction and Mental Health in Toronto from 1996-2003. Author of over 140 peer-reviewed papers, book chapters and government reports, Dr. Marsh’s research interests focus primarily on treatment of opioid dependence. Dr. Marsh received the Nyswander-Dole Award from the American Association for the Treatment of Opioid Dependence and Fellowships from the International and American Societies of Addiction Medicine in recognition of his contribution to this field.

Selected Research Grants and Awards

Pharmacogenetics of Methadone Maintenance Treatment Response.
PI: J. MacKillop, Z. Samaan Co-Investigators: D.C. Marsh, R. Palmer, G. Paré, L. Thabane, R.F. Tyndale.
Total Amount of Grant: $ 1,116,900 CAD

NOAMA Clinical Innovation Opportunities Fund
Evaluating the Impact of Methadone and Buprenorphine in Various Settings for Patients with
Opioid Use Disorder in Ontario, Canada
PI: D.C. Marsh Co-Investigators: J. Eibl, K. Morin, K. Quinlin
Total Amount of Grant: $ 50,000 CAD

Network Meta-Analysis of Opioid Agonist Treatments for street opioid users.
PI: N. Bansback, E. Oviedo-Joekes Co-Investigators: A. Anis, S. Brissette, D.C. Marsh, H. Palis, M.
Schecter, J. Westfall, W. Zhang.
Total Amount of Grant: $ 145,350 CAD

Program of Outcomes Research on Treatment with Injectables for Addiction (PORTIA).
PI: E. Oviedo-Joekes Co-Investigators: N. Bansback, S. Brissette, D. Byres, S. Harrison, A.
Janmohamed, D. MacDonald, K. Marchand, D.C. Marsh, H. Palis, M. Schecter, P. Spittal, M. Tyndall, J. Westfall.
Total Amount of Grant: $ 1,101,600 CAD

Evaluating the integration of Indigenous Healing with principals of Seeking safety for treatment
of Indigenous patients with a history of trauma and active substance use disorder.
PI: D.C. Marsh, C. Eshkakogan Co-Investigators: J. Eibl, T. Marsh, J. Walker
Total Amount of Grant: $ 150,000 CAD

Patient-Centered Care for Addictions Treatment: A Scoping Review.
PI: E. Oviedo-Joekes, S. Harrison Co-Investigators: D. MacDonald, K. Marchand, D.C. Marsh, M.
Schecter, J. Westfall.
Total Amount of Grant: $ 58,070 CAD

Impact of cannabis legalization on cannabis use and outcomes in patients with opioid use
disorder: a Canadian prospective cohort study.
PI: T. Rosic, Z. Samaan Co-Investigators: E. Lovell, J. MacKillop, D.C. Marsh, L. Thabane, L. Zielinski
Total Amount of Grant: $ 100,000 CAD

Selected Publications

Brittany B. Dennis, Daud Akhtar, George Cholankeril, Donghee Kim, Nitika Sanger, Alannah Hilmer, Caroul
Chawar, Alessia D’Elia, Balpreet Panesar, Andrew Worster, David C. Marsh, Lehana Thabane, Zainab Samaan and
Aijaz Ahmed. The Impact of Chronic Liver Disease in Patients receiving Active Pharmacological Therapy for
Opioid Use Disorder: One-Year Findings from a Prospective Cohort Study. Drug and Alcohol Dependence (2020)

Heather Palis, Kirsten Marchand, Scott Beaumont, Daphne Guh, Scott Harrison, Scott MacDonald, Suzanne
Brissette, David C. Marsh, Martin T. Schechter, and Eugenia Oviedo-Joekes. Physician Communication in
Injectable Opioid Agonist Treatment: Collecting Patient Ratings With the Communication Assessment Tool.
Journal of Addiction Medicine (2020)

Tea Rosic, Andrew Worster, Lehana Thabane, David C. Marsh and Zainab Samaan., Exploring psychological
symptoms and associated factors in patients receiving medication-assisted treatment for opioid-use disorder.
BJPsych Open (2020)

Heather McBrien, Candice Luo, Nitika Sanger, Laura Zielinski, Meha Bhatt, Xi Ming Zhu, David C. Marsh, Lehana
Thabane, Zainab Samaan. Cannabis use during methadone maintenance treatment for opioid use disorder: a
systematic review and meta-analysis. CMAJ Open (2019)

Dunn, K.E., Barrett, F.S., Brands, B., Marsh, D., Bigelow, G.E., Individual differences in self-reported human
opioid abuse potential as observed in a human laboratory study. Drug and Alcohol Dependence (2019)

Kirsten Marchand, Scott Beaumont, Jordan Westfall, Scott MacDonald, Scott Harrison, David C Marsh, Martin T
Schechter, Eugenia Oviedo-Joekes. Conceptualizing patient-centered care for substance use disorder treatment:
findings from a systematic scoping review. Substance Abuse Treatment, Prevention, and Policy (2019)

Kristen A Morin, Joseph K Eibl, Joseph M Caswell, Graham Gauthier, Brian Rush, Christopher Mushquash, Nancy
E Lightfoot, David C Marsh. Concurrent psychiatry for patients enrolled in opioid agonist treatment: a propensity
score matched cohort study in Ontario Canada. Substance Abuse Treatment, Prevention, and Policy (2019)

Ieta Shams, Nitika Sanger, Meha Bhatt, Tea Rosic, Candice Luo, Hamnah Shahid, Natalia, Mouravska, Sabrina Lue
Tam, Alannah Hillmer, Caroul Chawar, Alessia D’Elia, Jacqueline Hudson, David C Marsh, Lehana
Thabane and Zainab Samaan. The association between health conditions and cannabis use in patients with opioid
use disorder receiving methadone maintenance treatment. British Journal of Psychiatry Open (2019)

Eugenia Oviedo-Joekes, Heather Palis, Daphne Guh, Kristen Marchand, Suzanne Brissette, Scott Harrison, Scott
MacDonald, Kurt Lock, Aslam H. Anis, David C. Marsh, Martin T. Schechter. Treatment with injectable
hydromorphone: Comparing retention in double blind and open label treatment periods. Journal of Substance
Abuse Treatment (2019)

Oxana Mian, John C Hogenbirk, David C Marsh, Owen Prowse, Miriam Cain, Wayne Warry. Tracking Indigenous
Applicants Through the Admissions Process of a Socially Accountable Medical School. Academic Medicine

Eugenia Oviedo-Joekes, Heather Palis, Daphne Guh, David C. Marsh, Scott MacDonald, Scott Harrison, Suzanne
Brissette, Aslam H. Anis, Martin T. Schechter. Adverse Events During Treatment Induction With Injectable
Diacetylmorphine and Hydromorphone for Opioid Use Disorder. Journal of Addiction Medicine (2019)

Joseph K. Eibl, Andrew S Wilton, Alexandra M Franklyn, Paul Kurdyak, David C. Marsh. Evaluating the Impact
of Prescribed Versus Non-Prescribed Benzodiazepine Use in Methadone Maintenance Therapy: Results from a
Population-Based Retrospective Cohort Study. Journal of Addiction Medicine (2019)