Dr. Chris Verschoor
Dr. Verschoor research interests include:
- Chronic inflammation as a mechanism of age-related immune dysfunction and altered vaccine responses.
- Determinants of adverse health-related outcomes in older adults in community and clinical settings.
- Cellular and molecular biomarkers of disease and poor health trajectories.
- Development and application of measures of biological aging.
Recent Publications:
Verschoor CP, Lin DTS, Kobor MS, Mian O, Ma J, et al. Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging. Clinical Epigenetics. 2021. 13(1):163. PMID: 34425884.
Picard E, Bowdish DME, McElhaney JE, Pawelec G, Loeb M, Verschoor CP. The frequency of interleukin-1β-producing monocytes is significantly associated with varicella-zoster responses of nursing home residents. Clinical and Experimental Immunology. 2021. 205(1):63-74. PMID: 33714219.
Verschoor CP, Belsky DW, Ma J, Cohen AA, Griffith L et al. Comparing biological age estimates using domain-specific measures from the Canadian Longitudinal Study on Aging. J Gerontol A Biol Sci Med Sci. 2021. 76(2):187-194. PMID: 32598446.
McHugh J, Duong M, Ma J, Dales RE, Bassim CW, and Verschoor CP. A comprehensive analysis of factors related to lung function in older adults: cross-sectional findings from the Canadian Longitudinal Study on Aging. Respir Med. 2020. 173:106157. PMID: 33010732.
Loeb N, Andrew MK, Loeb M, Kuchel GA, Haynes L, McElhaney JE, and Verschoor CP. Frailty is associated with increased hemagglutinin-inhibition titres in a 4-year randomized trial comparing standard and high dose influenza vaccination. Open Forum Infect Dis. 2020. 7(5):ofaa148. PMID: 32500087.
Verschoor CP and Tamim H. Frailty is inversely related to age at menopause and elevated in women who have had a hysterectomy: an analysis of the Canadian Longitudinal Study on Aging. Journal of Gerontology: Series A – Medical Sciences. 2019. 74(5):675-682. PMID: 29688443.
Verschoor CP and Kohli V. Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-colour flow cytometry. Cytometry: Part A. 2018. 93(5):548-555. PMID: 29624852.
Verschoor CP, Lelic A, Parsons R, Evelegh C, Bramson JL, et al. Serum C-reactive protein and congestive heart failure are significant predictors of the herpes-zoster vaccine response in the nursing home elderly. Journal of Infectious Diseases. 2017. 216(2):191-197. PMID: 28838148.
Funded Projects:
An epigenetic “inflammaging” score (EIS) as a tool to quantify healthy aging and predict adverse health outcomes in older adults. Verschoor CP (NPI), Conlon M, Pare G, Ritz S, Ma J, Ybazeta G. Canadian Institutes of Health Research (CIHR), Catalyst Grant: Analysis of CLSA Data. 2020-2021.
Examining the relationship between biological age and influenza vaccine responses in older adults. Verschoor CP (NPI), McElhaney J, Loeb M. Lung Health Foundation Breathing as One Young Investigator Research Award. 2020-2021.
Chronic inflammation as a determinant of influenza vaccine efficacy and respiratory outcomes in older adults. Verschoor CP (NPI), McElhaney J, Loeb M. Ontario Lung Association/Ontario Thoracic Society, Lung Health Foundation Team Breathe Research Award. 2020-2021.
Health-age: a composite biomarker measure to estimate healthy aging in older Canadians. Verschoor CP (NPI), Belsky DW, Cohen AA, and co-investigators. Canadian Institutes of Health Research (CIHR), Catalyst Grant: Analysis of CLSA Data. 2019-2020.