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Dr. Ioannis Voutsadakis

Recent Projects:

Pre-treatment platelet counts as a prognostic and predictive factor in stage II and III rectal adenocarcinoma (2015)

Learner involved: Morgan Steele, Algoma University student
Support: Sault Ste Marie Academic Association (SSMAMA) grant 

Steele M, Voutsadakis IA. Pre-treatment platelet counts as a prognostic and predictive factor in stage II and III rectal adenocarcinoma. World J Gastrointest Oncol 2017; 9: 42-49 

Voutsadakis IA, Steele M. Pre-treatment platelet counts as prognostic factor in stage II and III rectal adenocarcinoma. Annual Meeting of the American Association for Cancer Research, New Orleans, LA, April 16-20, 2016, Cancer Res 2016; (Suppl.) 


Docetaxel-Associated Myalgia-Arthralgia Syndrome in Patients with Breast Cancer (2015) 

Learner involved: Chelsea Seguin, Algoma University Nursing student
Support: Sault Ste Marie Academic Association (SSMAMA) grant 

Seguin C, Kovacevich N, Voutsadakis IA. Docetaxel-Associated Myalgia-Arthralgia Syndrome in Patients with Breast Cancer. Breast Cancer: Targets and Therapy 2017; 9: 39-44 

Voutsadakis IA, Seguin C. Taxanes–associated myalgia-arthralgia syndrome in patients with breast cancer. European Breast Cancer Conference, Amsterdam, The Netherlands, March 9-11, 2016, Eur J Cancer 2016; 57(Suppl. 2): S94 

Peripheral blood neutrophils, lymphocytes, and platelet counts at diagnosis as prognostic markers in metastatic colorectal cancer patients (2017) 

Learner involved: Joey Mercier, NOSM medical student
Support: Dean’s Summer research student award 

Mercier J, Voutsadakis IA. The platelets-neutrophils to lymphocytes ratio: A new prognostic marker in metastatic colorectal cancer. J Gastrointest Oncol 2018; 9: 478-486 

Mercier J, Voutsadakis IA. Comparison of hematologic and other prognostic markers in metastatic colorectal cancer. J Gastrointest Cancer 2018 (Epub ahead of print) 

Mercier J, Voutsadakis IA. Investigation of peripheral blood neutrophils, lymphocytes, and platelet counts at diagnosis as prognostic markers in metastatic colorectal cancer patients. Northern Health Research Conference, Thunder Bay, ON, October 13-14, 2017. 

The Oncotype Dx assay in the treatment of ER+, Her2-, lymph node- breast cancer patients (2017) 

Learner involved: Stephane Thibodeau, NOSM medical student
Support: Dean’s Summer research student award 

Thibodeau S, Voutsadakis IA. Prediction of the Oncotype Dx recurrence score using clinical parameters: A comparison of available tools and a simple predictor based on grade and progesterone receptor. Hematol Oncol Stem Cell Ther 2019 (Epub ahead of print) 

Thibodeau S, Voutsadakis IA. The Oncotype Dx assay in ER-positive, HER2-negative breast cancer patients: A real life experience from a single cancer center. Eur J Breast Health 2019 (accepted) 

Thibodeau S, Voutsadakis IA. Influence and associations of the Oncotype Dx assay in the treatment of ER+, Her2-, lymph node- breast cancer patients: A single center experience. Northern Health Research Conference, Thunder Bay, ON, October 13-14, 2017 

Voutsadakis IA, Thibodeau S, Reed M. Prediction of the Oncotype Dx Recurrence Score (RS) from clinicopathologic factors. San Antonio Breast Cancer Symposium, San Antonio, TX, December 4-8, 2018. 

Prediction of Hospital Admissions and Grade 3-4 Toxicities in Cancer Patients 70 Years-old and Older Receiving Chemotherapy (2017-18) 

Learner involved: Melissa Reed, Algoma University psychology student
Support: Sault Ste Marie Academic Association (SSMAMA) grant 

Reed M, Patrick C, Quevillon T, Walde N, Voutsadakis IA. Prediction of hospital admissions and grade 3-4 toxicities in cancer patients 70 years-old and older receiving chemotherapy. Eur J Cancer Care 2019 (in revision) 

Reed M, Patrick C, Quevillon T, Walde N, Voutsadakis IA. Prediction of Hospital Admissions and Grade 3-4 Toxicities in Cancer Patients 70 Years-old and Older Receiving Chemotherapy. Palliative and Supportive Care in Oncology Symposium (ASCO, ASTRO, MSCC), San Diego, CA, November 16-17, 2018. 

An assessment of baseline staging tests in primary breast cancer in a community setting (2017-18) 

Learner involved: Lily DeMiglio and Jeannie Murdoch, NOSM Family Medicine Residents
Support: none, project done as a requirement for residency 

DeMiglio L, Murdoch J, Voutsadakis IA. An assessment of baseline staging tests in primary breast cancer in a community setting in Northern Ontario. Northern Health Research Conference, Thunder Bay, ON, October 13-14, 2017. 

DeMiglio L, Murdoch J, Ivison J, Voutsadakis IA. Adherence to guidelines for baseline staging in newly diagnosed localized breast cancer (paper submitted) 

Platelet and neutrophil counts as predictive markers of neoadjuvant therapy efficacy in rectal cancer (2018) 

Learner involved: AnnaLee Policicchio, NOSM medical student
Support: Dean’s Summer research student award 

Policicchio A, Mercier J, Digklia A, Voutsadakis IA. Platelet and neutrophil counts as predictive markers of neoadjuvant therapy efficacy in rectal cancer. J Gastrointest Cancer 2018 (Epub ahead of print) 

Evaluation of chromosome 17 centromere amplification in breast cancer (2019 in progress) 

Learner involved: Vanessa Davis, NOSM medical student
Support: Dean’s Summer research student award

Funded Projects:

Taxanes–associated myalgia-arthralgia syndrome in patients with breast cancer: Sault Ste Marie Academic Medical Association, Ontario, Canada (2015). 

Pre-treatment platelet counts as prognostic factor in stage II and II rectal adenocarcinoma: Sault Ste Marie Academic Medical Association, Ontario, Canada (2015).

Prognostic associations of diabetes and obesity in patients with colorectal cancer. Sault Ste Marie Academic Medical Association, Ontario, Canada (2016).

Prediction of chemotherapy toxicity in older cancer patients. Sault Ste Marie Academic Medical Association, Ontario, Canada (2017). 

Development, validation and implementation of a practical clinical tool for prediction of chemotherapy toxicity in older cancer patients treated in a community cancer clinic of the North. Northern Ontario Academic Medical Association, Ontario, Canada (2018). 

Systemic effect of Radiation therapy in cancer patients receiving immune blockade inhibitors: Role of dose, fractionation and time. Sault Ste Marie Academic Medical Association, Ontario, Canada (2018). 

Investigation of Tumor budding at diagnosis as a prognostic marker in locally advanced breast cancer. Sault Ste Marie Academic Medical Association, Ontario, Canada (2018).